P2.03b-074 NSCLC Homing Nanoparticles Selectively Transfect Lung Cancer
نویسندگان
چکیده
منابع مشابه
Nanoparticles of compacted DNA transfect postmitotic cells.
Charge-neutral DNA nanoparticles have been developed in which single molecules of DNA are compacted to their minimal possible size. We speculated that the small size of these DNA nanoparticles may facilitate gene transfer in postmitotic cells, permitting nuclear uptake across the 25-nm nuclear membrane pore. To determine whether DNA nanoparticles can transfect nondividing cells, growth-arrested...
متن کامل[Non-small cell lung cancer (NSCLC)].
The goal of radiation therapy for non-small cell lung cancer (NSCLC) is to improve the survival rate of patients without increasing treatment-related toxicity and to improve patients' quality of life. Several prospective randomized trials have demonstrated a survival advantage in combined modality treatment over radiotherapy or chemotherapy alone when a cisplatin-based chemotherapy regimen is u...
متن کاملMulticomponent, Tumor-Homing Chitosan Nanoparticles for Cancer Imaging and Therapy
Current clinical methods for cancer diagnosis and therapy have limitations, although survival periods are increasing as medical technologies develop. In most cancer cases, patient survival is closely related to cancer stage. Late-stage cancer after metastasis is very challenging to cure because current surgical removal of cancer is not precise enough and significantly affects bystander normal t...
متن کاملHealth Organization (WHO) classification, lung cancer can be divided into two major classes: small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). NSCLC
It is known that the cause of cancer could be due to the gain of function of an oncoprotein (OCP) or the lost of function of a tumor suppressor protein (TSP). These proteins are potential targets for drugs. Lung cancer is one of the leading causes of death in Taiwan. In this study, differential expressed genes (DEGs) are identified, using the Bioconductor package, via expression dataset generat...
متن کاملA review of the role of dopamine receptors and novel therapeutic strategies in non-small cell lung cancer (NSCLC)
Lung cancer is a very aggressive and most deadly cancer in both men and women. Lung cancer is divided into two types of small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). NSCLC is divided into 3 subgroups: adenocarcinoma (AC), squamous cell carcinoma (SqCC) and large cell carcinoma (LCC). Dopamine is involved in controlling motions, cognition, emotions, memory and reward mech...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Thoracic Oncology
سال: 2017
ISSN: 1556-0864
DOI: 10.1016/j.jtho.2016.11.1356